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Review
10.
Application of monoclonal antibodies in veterinary
parasitology -
A. Gupta, A. K. Dixit, Pooja Dixit, Chetana
Mahajan
Vet World. 2011; 4(4): 183-188
doi:
10.5455/vetworld.2011.183-188
Abstract
The discovery of hybridoma technology by Kohler
and Milstein in 1975, heralded a new era in
antibody research. Mouse hybridomas were the first
reliable source of monoclonal antibodies. The
generation of monoclonal antibodies from species
other than rats and mice, has developed slowly
over the last 30 years. The advent of antibody
engineering and realization of the advantages of
non murine antibodies has increased their
relevance recently. However, in the area of
veterinary parasitology, monoclonal antibodies are
just beginning to fulfill the promises inherent in
their great specificity for recognizing and
selectively binding to antigens. This review
describes the recent advances in the application
of monoclonal antibodies for immunodiagnosis /
prophylaxis and immunotherapy of parasitic
diseases.
Keywords: Coccidiosis,
Fasciolosis, Immunodiagnosis, Immunotherapy,
Monoclonal antibody, Vaccine, Parasite,
Parasitology, Hybridoma.
